Matthew L. Dennis

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Jonathan B. Baell, David J. Leaver, S.J. Hermans et al. · Nature · 2018 · 300 citations · Full text

Cancer Research, Chromatin, Tumour Growth +12

HBO1 is required for the maintenance of leukaemia stem cells

Laura MacPherson, Juliana Anokye, Miriam M. Yeung et al. · Nature · 2019 · 170 citations · Full text

Medicine, Stem Cell Mobilization, Leukaemia Stem Cells +7

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer

Shikhar Sharma, Chi‐Yeh Chung, Sean Uryu et al. · Cell chemical biology · 2023 · 59 citations · Full text

8‐Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase

Matthew L. Dennis, Michael D. Lee, Jitendra R. Harjani et al. · Chemistry - A European Journal · 2017 · 55 citations

Crystal structures of human ENPP1 in apo and bound forms

Matthew L. Dennis, Janet Newman, Olan Dolezal et al. · Acta Crystallographica Section D Structural Biology · 2020 · 42 citations · Full text

Molecular Biology, Immune System, Chemical Biology +16