Pascale G. Charest

β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

Mounia Azzi, Pascale G. Charest, Stéphane Angers et al. · Proceedings of the National Academy of Sciences · 2003 · 504 citations · Full text

G protein–independent Ras/PI3K/F-actin circuit regulates basic cell motility

Atsuo T. Sasaki, Chris Janetopoulos, Susan Lee et al. · The Journal of Cell Biology · 2007 · 239 citations · Full text

Monitoring agonist‐promoted conformational changes of β‐arrestin in living cells by intramolecular BRET

Pascale G. Charest, Sonia Terrillon, Michel Bouvier · EMBO Reports · 2005 · 170 citations · Full text

Molecular Pharmacology, Signal Transduction, Biochemistry +12

Incoherent Feedforward Control Governs Adaptation of Activated Ras in a Eukaryotic Chemotaxis Pathway

Kosuke Takeda, Danying Shao, Micha Adler et al. · Science Signaling · 2012 · 166 citations · Full text

Activated Ras, Molecular Biology, Perfect Adaptation +22

A Ras Signaling Complex Controls the RasC-TORC2 Pathway and Directed Cell Migration

Pascale G. Charest, Zhouxin Shen, Ashley M. Lakoduk et al. · Developmental Cell · 2010 · 157 citations · Full text

Signal Transduction, Rasc-torc2 Pathway, Cell Regulation +9