Christine M. Bowman

Loss-of-function HDAC8 mutations cause a phenotypic spectrum of Cornelia de Lange syndrome-like features, ocular hypertelorism, large fontanelle and X-linked inheritance

Frank J. Kaiser, Morad Ansari, Diana Braunholz et al. · Human Molecular Genetics · 2014 · 146 citations · Full text

Genetics, Immunodeficiencies, Genetic Epidemiology +27

Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders

Christophe Decroos, Christine M. Bowman, J. Moser et al. · ACS Chemical Biology · 2014 · 67 citations · Full text

Molecular Regulation, Genetics, Molecular Biology +18

General Base–General Acid Catalysis in Human Histone Deacetylase 8

Sister M. Lucy Gantt, Christophe Decroos, Matthew S. Lee et al. · Biochemistry · 2016 · 67 citations · Full text

Histone Modifications, Chromatin, Histone Deacetylases +14

The Pharmacokinetics and Efficacy of an Aminoglycoside Administered into the Cerebral Ventricles in Neonates: Implications for Further Evaluation of This Route of Therapy in Meningitis

Peter F. Wright, Allen B. Kaiser, Christine M. Bowman et al. · The Journal of Infectious Diseases · 1981 · 64 citations

Further Evaluation, Aminoglycoside Administered, Optimal Dose +13

In Vitro-In Vivo Extrapolation and Hepatic Clearance-Dependent Underprediction

Christine M. Bowman, Leslie Z. Benet · Journal of Pharmaceutical Sciences · 2019 · 62 citations · Full text

Vitro-in Vivo Extrapolation, Hepatology, Liver Physiology +9