Christophe Decroos

HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle

Matthew A. Deardorff, Masashige Bando, Ryuichiro Nakato et al. · Nature · 2012 · 576 citations · Full text

Life Sciences, Genetics, Molecular Biology +8

Loss-of-function HDAC8 mutations cause a phenotypic spectrum of Cornelia de Lange syndrome-like features, ocular hypertelorism, large fontanelle and X-linked inheritance

Frank J. Kaiser, Morad Ansari, Diana Braunholz et al. · Human Molecular Genetics · 2014 · 152 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

General Base–General Acid Catalysis in Human Histone Deacetylase 8

Sister M. Lucy Gantt, Christophe Decroos, Matthew S. Lee et al. · Biochemistry · 2016 · 68 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders

Christophe Decroos, Christine M. Bowman, J. Moser et al. · ACS Chemical Biology · 2014 · 67 citations

Life Sciences, Genetics, Molecular Biology +13

Variable Active Site Loop Conformations Accommodate the Binding of Macrocyclic Largazole Analogues to HDAC8

Christophe Decroos, Dane J. Clausen, Brandon E. Haines et al. · Biochemistry · 2015 · 56 citations

Medicine, Medicinal Chemistry, Pharmacology +15