Concepedia

Aroop Sircar

AS

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Publications

11

Citations

1.4K

H-Index

11

Active since

2007

Affiliations

Johns Hopkins University(Current)

University of North Carolina at Chapel Hill

Ono Pharmaceutical (United States)

Merck Serono S.p.A. (Italy)

Aroop Sircar is an author at Johns Hopkins University specializing in life sciences, structural biology, and protein structure.

Publications per year

2007–2022

11

Publications

11

Enhanced preclinical antitumor activity of M7824, a bifunctional fusion protein simultaneously targeting PD-L1 and TGF-β

Yan Lan, Dong Zhang, Chunxiao Xu et al. · Science Translational Medicine · 2018 · 488 citations

Life Sciences, Immunology, Oncology +17

Toward high‐resolution homology modeling of antibody F<sub>v</sub> regions and application to antibody–antigen docking

Arvind Sivasubramanian, Aroop Sircar, Sidhartha Chaudhury et al. · Proteins Structure Function and Bioinformatics · 2008 · 188 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

SnugDock: Paratope Structural Optimization during Antibody-Antigen Docking Compensates for Errors in Antibody Homology Models

Aroop Sircar, Jeffrey J. Gray · PLoS Computational Biology · 2010 · 186 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17

Structure-Based Design of Supercharged, Highly Thermoresistant Antibodies

Aleksandr E. Miklos, Christien Kluwe, Bryan S. Der et al. · Chemistry & Biology · 2012 · 142 citations

Pharmacy, Biochemistry, Molecular Biology +14

Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology

Sarel J. Fleishman, Timothy A. Whitehead, Eva‐Maria Strauch et al. · Journal of Molecular Biology · 2011 · 136 citations · Full text

Life Sciences, Bioinformatics, Computational Biology +15

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