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Progressive Transforming Growth Factor β1–induced Lung Fibrosis Is Blocked by an Orally Active ALK5 Kinase Inhibitor

Philippe Bonniaud, Peter J. Margetts, Martin Kolb et al. · American Journal of Respiratory and Critical Care Medicine · 2004 · 252 citations

Fibrosis, Inflammatory Lung Disease, Lung Inflammation +15

Inhibition of Growth and Metastasis of Mouse Mammary Carcinoma by Selective Inhibitor of Transforming Growth Factor-β Type I Receptor Kinase <i>In vivo</i>

Rongrong Ge, Vaishali Rajeev, Partha Ray et al. · Clinical Cancer Research · 2006 · 152 citations

Targeting Endogenous Transforming Growth Factor β Receptor Signaling in SMAD4-Deficient Human Pancreatic Carcinoma Cells Inhibits Their Invasive Phenotype

Gayathri Subramanian, Roderich E. Schwarz, Linda S. Higgins et al. · Cancer Research · 2004 · 134 citations

2-Azetidinone Cholesterol Absorption Inhibitors:  Structure−Activity Relationships on the Heterocyclic Nucleus

John W. Clader, Duane A. Burnett, Mary Ann Caplen et al. · Journal of Medicinal Chemistry · 1996 · 133 citations

Medicinal Chemistry, Heterocyclic, Pharmacological Study +14

p38α-Selective Mitogen-Activated Protein Kinase Inhibitor SD-282 Reduces Inflammation in a Subchronic Model of Tobacco Smoke-Induced Airway Inflammation

Satyanarayana Medicherla, Mary F. Fitzgerald, Dianne Spicer et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 94 citations