Effect of Plasmid DNA Vaccine Design and In Vivo Electroporation on the Resulting Vaccine-Specific Immune Responses in Rhesus Macaques

Amara Luckay, Maninder K. Sidhu, Rune Kjeken, +14

Journal of Virology

ImmunologyHuman Immunodeficiency VirusImmunotherapyVivo ElectroporationRhesus Macaques +15

Coimmunization with an Optimized IL-15 Plasmid Results in Enhanced Function and Longevity of CD8 T Cells That Are Partially Independent of CD4 T Cell Help

Michele A. Kutzler, Tara M. Robinson, Michael A. Chattergoon, +15

The Journal of Immunology

Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine

Ye Che, Alexey V. Gribenko, Xi Song, +19

Science Translational Medicine

VaccinationRsv FusionVaccine DevelopmentAllergyRational Design +10

A dose sparing effect by plasmid encoded IL-12 adjuvant on a SIVgag-plasmid DNA vaccine in rhesus macaques

Eva B. Schadeck, Maninder K. Sidhu, Michael A. Egan, +14

Vaccine

VaccinationSivgag-plasmid Dna VaccineVaccine DevelopmentRhesus MacaquesVaccine Target +5

Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines

Rong Xu, Shakuntala Megati, Vidia Roopchand, +10

Vaccine

VaccinationMucosal VaccinationComparative AbilityVarious Plasmid-based CytokinesImmunology +7

Rational design of a plasmid DNA vaccine capable of eliciting cell-mediated immune responses to multiple HIV antigens in mice

Michael A. Egan, Shakuntala Megati, Vidia Roopchand, +11

Vaccine

VaccinationMucosal VaccinationVaccine DevelopmentRational DesignImmunology +7

Modifying the HIV-1 env gp160 gene to improve pDNA vaccine-elicited cell-mediated immune responses

Shakuntala Megati, Dorys Garcia-Hand, Sarah Cappello, +15

Vaccine

Human RetrovirusImmunologyAntiviral ResponseChronic Viral InfectionVaccine Design +3

Non-propagating, recombinant vesicular stomatitis virus vectors encoding respiratory syncytial virus proteins generate potent humoral and cellular immunity against RSV and are protective in mice

J. Erik Johnson, Lisa K. McNeil, Shakuntala Megati, +11

Immunology Letters

Viral ReplicationRespiratory Virus ImmunitySynthetic VirologyRespiratory DiseasesImmunology +8

Nonreplicating Vaccines Can Protect African Green Monkeys From the Memphis 37 Strain of Respiratory Syncytial Virus

Jim Eyles, James E. Johnson, Shakuntala Megati, +20

The Journal of Infectious Diseases