Concepedia

Laurie A. LeBrun

LA

Statistics

Publications

33

Citations

1.7K

H-Index

23

Active since

1999

Affiliations

University of Iowa(Current)

Bristol-Myers Squibb (United States)

University of California, San Francisco

Unisys (United States)

Laurie A. LeBrun is an author at University of Iowa specializing in life sciences, medicinal chemistry, and drug discovery.

Publications per year

1999–2021

33

Publications

33

A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos

Mary E. Matyskiela, Weihong Zhang, Hon‐Wah Man et al. · Journal of Medicinal Chemistry · 2017 · 291 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Discovery of CRBN E3 Ligase Modulator CC-92480 for the Treatment of Relapsed and Refractory Multiple Myeloma

Joshua D. Hansen, Matthew Correa, Mark A. Nagy et al. · Journal of Medicinal Chemistry · 2020 · 218 citations · Full text

Medicine, Oncology, Pharmacology +13

CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia

Joshua D. Hansen, Matthew Correa, Matt Alexander et al. · Journal of Medicinal Chemistry · 2021 · 149 citations · Full text

Medicine, Medicinal Chemistry, Oncology +13

Interaction of the N-Terminal Domain of Apolipoprotein E4 with Heparin

Jun Dong, Clare Peters‐Libeu, Karl H. Weisgraber et al. · Biochemistry · 2001 · 101 citations

Life Sciences, Biochemistry, Molecular Biology +9

Protein Degradation via CRL4<sup>CRBN</sup> Ubiquitin Ligase: Discovery and Structure–Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1

Joshua D. Hansen, Kevin R. Condroski, Matthew Correa et al. · Journal of Medicinal Chemistry · 2017 · 76 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

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