Kevin R. Condroski

RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies

Benjamin Solomon, Lavinia Tan, Stephen Q. Wong et al. · Journal of Thoracic Oncology · 2020 · 284 citations · Full text

Medicine, Oncology, Pharmacology +17

Transition States of Epoxidations:  Diradical Character, Spiro Geometries, Transition State Flexibility, and the Origins of Stereoselectivity

K. N. Houk, Jian Liu, Nicholas C. DeMello et al. · Journal of the American Chemical Society · 1997 · 174 citations

Natural Sciences, Chemistry, Computational Chemistry +11

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)

Scott D. Seiwert, Steven W. Andrews, Yutong Jiang et al. · Antimicrobial Agents and Chemotherapy · 2008 · 174 citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

Discovery of Danoprevir (ITMN-191/R7227), a Highly Selective and Potent Inhibitor of Hepatitis C Virus (HCV) NS3/4A Protease

Yutong Jiang, Steven W. Andrews, Kevin R. Condroski et al. · Journal of Medicinal Chemistry · 2013 · 142 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Radical and Concerted Mechanisms in Oxidations of Amines, Sulfides, and Alkenes by Peroxynitrite, Peroxynitrous Acid, and the Peroxynitrite−CO₂ Adduct:  Density Functional Theory Transition Structures and Energetics

K. N. Houk, Kevin R. Condroski, William A. Pryor · Journal of the American Chemical Society · 1996 · 112 citations

Natural Sciences, Chemistry, Computational Chemistry +15