Jonathan V. Pascale

Sequencing of 640,000 exomes identifies <i>GPR75</i> variants associated with protection from obesity

Parsa Akbari, Ankit Gilani, Olukayode Sosina et al. · Science · 2021 · 276 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Uncovering the signalling, structure and function of the 20‐HETE‐GPR75 pairing: Identifying the chemokine CCL5 as a negative regulator of GPR75

Jonathan V. Pascale, Eon Joo Park, Adeniyi Michael Adebesin et al. · British Journal of Pharmacology · 2021 · 55 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

20-HETE interferes with insulin signaling and contributes to obesity-driven insulin resistance

Ankit Gilani, Kevin Agostinucci, Sakib Hossain et al. · Prostaglandins & Other Lipid Mediators · 2020 · 39 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +14

<scp>Gpr75</scp>‐deficient mice are protected from high‐fat diet–induced obesity

Sakib Hossain, Ankit Gilani, Jonathan V. Pascale et al. · Obesity · 2023 · 39 citations · Full text

Medicine, Endocrinology, Molecular Genetics +17

Unbiased proteomics identifies plasminogen activator inhibitor-1 as a negative regulator of endothelial nitric oxide synthase

Víctor Garcia, Eon Joo Park, Mauro Siragusa et al. · Proceedings of the National Academy of Sciences · 2020 · 38 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15