Celia Sigua

Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3

Prince George, Purva Bali, Srinivas Annavarapu et al. · Blood · 2004 · 322 citations

Cotreatment with Histone Deacetylase Inhibitor LAQ824 Enhances Apo-2L/Tumor Necrosis Factor-Related Apoptosis Inducing Ligand-Induced Death Inducing Signaling Complex Activity and Apoptosis of Human Acute Leukemia Cells

Fei Guo, Celia Sigua, Jianguo Tao et al. · Cancer Research · 2004 · 201 citations

Cinnamic Acid Hydroxamate, Hematological Malignancy, Cell Signaling +12

Mechanistic role of heat shock protein 70 in Bcr-Abl–mediated resistance to apoptosis in human acute leukemia cells

Fei Guo, Celia Sigua, Purva Bali et al. · Blood · 2004 · 173 citations · Full text

Superior Activity of the Combination of Histone Deacetylase Inhibitor LAQ824 and the FLT-3 Kinase Inhibitor PKC412 against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3

Purva Bali, Prince George, Pamela Cohen et al. · Clinical Cancer Research · 2004 · 124 citations · Full text

Cotreatment with 17-Allylamino-Demethoxygeldanamycin and FLT-3 Kinase Inhibitor PKC412 Is Highly Effective against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3

Prince George, Purva Bali, Pamela Cohen et al. · Cancer Research · 2004 · 122 citations · Full text

Hematological Malignancy, Length Mutation, Medicine +15