Concepedia

Juan F. Rodríguez-Alcázar

JF

6

Publications

315

Citations

6

H-Index

2018

Active since

Affiliations

University of Bonn(Current)

University of Massachusetts Chan Medical School

University Hospital Bonn

University of California San Diego

German Center for Neurodegenerative Diseases

Juan F. Rodríguez-Alcázar is an author at University of Bonn specializing in cell signaling, medicine, and innate immunity.

Top concepts

MedicineCell SignalingCell BiologyInnate ImmunityNatural SciencesMolecular BiologySignal TransductionCellular BiochemistryLupusImmunology

Publications per year

2018–2025

6

Publications

6

Charcot–Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1β Inflammation in Human Macrophages

Juan F. Rodríguez-Alcázar, Marco A. Ataide, Gudrun Engels et al. · The Journal of Immunology · 2018 · 71 citations · Full text

Alternative splicing regulates stochastic NLRP3 activity

James L. Mueller, Francisca Rojas, Juan F. Rodríguez-Alcázar et al. · Nature Communications · 2019 · 66 citations · Full text

Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation

Inga V. Hochheiser, Heide Behrmann, Gregor Hagelueken et al. · Science Advances · 2022 · 61 citations · Full text

Protein Assembly, Molecular Biology, Filament Growth +17

ATP-binding and hydrolysis of human NLRP3

Rebecca Brinkschulte, David Fusshöller, Juan F. Rodríguez-Alcázar et al. · Communications Biology · 2022 · 60 citations · Full text

Protein Function, Signal Transduction, Biochemistry +13

NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression

Róisín M. McManus, Max P. Komes, Angelika Griep et al. · Immunity · 2025 · 30 citations

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