Paloma Liras

A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds

Francisco José Pérez-Llarena, Paloma Liras, Antonio Rodríguez‐García · Journal of Bacteriology · 1997 · 154 citations · Full text

Engineering, Bacteriology, Cephamycin Gene Cluster +16

Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus

Rubén Álvarez-Álvarez, Alma Botas, Silvia M. Albillos et al. · Microbial Cell Factories · 2015 · 127 citations · Full text

Dissociation of cephamycin and clavulanic acid biosynthesis in Streptomyces clavuligerus

Paloma Liras, J. F. Mart�n · Applied Microbiology and Biotechnology · 1984 · 124 citations

Biosynthesis, Biotransformation, Biochemistry +3

The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum

Juan José R. Coque, Javier Calzada, Paloma Liras · Molecular Microbiology · 1991 · 115 citations

Genes for a beta-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans.

Juan José R. Coque, Paloma Liras · The EMBO Journal · 1993 · 107 citations · Full text

Antimicrobial Resistance Gene, Health Sciences, Antibiotics +12