Francisco José Pérez-Llarena

OXA-235, a Novel Class D β-Lactamase Involved in Resistance to Carbapenems in Acinetobacter baumannii

Paul G. Higgins, Francisco José Pérez-Llarena, Esther Zander et al. · Antimicrobial Agents and Chemotherapy · 2013 · 209 citations · Full text

Bacteriology, Antibiotic Resistance, United States +18

A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds

Francisco José Pérez-Llarena, Paloma Liras, Antonio Rodríguez‐García · Journal of Bacteriology · 1997 · 154 citations · Full text

Engineering, Bacteriology, Cephamycin Gene Cluster +16

Characterization of the cmcH genes of Nocardia lactamdurans and streptomyces clavuligerus encoding a functional 3'-hydroxymethylcephem O-carbamoyltransferase for cephamycin biosynthesis

Juan José R. Coque, Francisco José Pérez-Llarena, Francisco J. Enguita et al. · Gene · 1995 · 54 citations

Biosynthesis, Biotransformation, Biochemistry +9

The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity

Francisco José Pérez-Llarena, Moreno Galleni, Juan José R. Coque et al. · Journal of Bacteriology · 1997 · 46 citations · Full text

Biosynthesis, Antibiotics, Biochemistry +14

The <i>pcd</i> Gene Encoding Piperideine-6-Carboxylate Dehydrogenase Involved in Biosynthesis of α-Aminoadipic Acid Is Located in the Cephamycin Cluster of <i>Streptomyces clavuligerus</i>

Francisco José Pérez-Llarena, Antonio Rodríguez‐García, Francisco J. Enguita et al. · Journal of Bacteriology · 1998 · 37 citations · Full text

Streptomyces Proteins, Bacteriology, Molecular Biology +18