Concepedia

Georges Hirth

GH

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Publications

13

Citations

1.8K

H-Index

13

Active since

1982

Affiliations

Roche (Switzerland)(Current)

Actelion (Switzerland)

Rheinmetall (Switzerland)

Georges Hirth is an author at Roche (Switzerland) specializing in medicine, pharmacology, and biochemistry.

Top concepts

Publications per year

1982–1999

13

Publications

13

Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist.

Martine Clozel, Volker Breu, Gillian A. Gray et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 667 citations

Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist

Martine Clozel, Volker Breu, Kaspar F. Burri et al. · Nature · 1993 · 529 citations

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Renin inhibition by substituted piperidines: A novel paradigm for the inhibition of monomeric aspartic proteinases?

Christian Oefner, Alfred Binggeli, Volker Breu et al. · Chemistry & Biology · 1999 · 126 citations · Full text

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Substituted piperidines - highly potent renin inhibitors due to induced fit adaptation of the active site

Eric Vieira, Alfred Binggeli, Volker Breu et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 95 citations · Full text

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Synthese von Glycerylätherphosphatiden 1. Mitteilung Herstellung von 1‐<i>O</i>‐Octadecyl‐2‐<i>O</i>‐acetyl‐sn‐glyceryl‐3‐phosphorylcholin<sup>1</sup> (‘Platelet Activating Factor’), des Enantiomeren sowie einiger analoger Verbindungen

Georges Hirth, R. Barner · Helvetica Chimica Acta · 1982 · 94 citations

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