Adrian Kwan Ho Loe

PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance

Meryem B. Baghdadi, Ronja M. Houtekamer, Louisiane Perrin et al. · Science · 2024 · 74 citations · Full text

Engineering, Adult Stem Cell, Mechanotransduction +21

Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development

Ji‐Eun Kim, Bo Li, Lijiang Fei et al. · Immunity · 2022 · 68 citations

Dysbiosis, Developmental Biology, Early Postnatal Development +11

Uncovering the dosage-dependent roles of <i>Arid1a</i> in gastric tumorigenesis for combinatorial drug therapy

Adrian Kwan Ho Loe, Roshane Francis, Jieun Seo et al. · The Journal of Experimental Medicine · 2021 · 26 citations · Full text

Pathology, Pharmacotherapy, Gc Cells +20

Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes

Sinthu Pathmanapan, Olga Ilkayeva, John T. Martin et al. · Cancer & Metabolism · 2021 · 22 citations · Full text

Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation

Sinthu Pathmanapan, Raymond Poon, Tomasa Barrientos De Renshaw et al. · Cell Reports · 2023 · 17 citations · Full text