Wei‐Ru Huang

The p17 Nonstructural Protein of Avian Reovirus Triggers Autophagy Enhancing Virus Replication via Activation of Phosphatase and Tensin Deleted on Chromosome 10 (PTEN) and AMP-activated Protein Kinase (AMPK), as well as dsRNA-dependent Protein Kinase (PKR)/eIF2α Signaling Pathways

Pei I., Wei‐Ru Huang, IH. Lai et al. · Journal of Biological Chemistry · 2012 · 93 citations · Full text

P17 Nonstructural Protein, Viral Replication, Molecular Virology +12

Cell Entry of Avian Reovirus Follows a Caveolin-1-mediated and Dynamin-2-dependent Endocytic Pathway That Requires Activation of p38 Mitogen-activated Protein Kinase (MAPK) and Src Signaling Pathways as Well as Microtubules and Small GTPase Rab5 Protein

Wei‐Ru Huang, Ying C. Wang, Pei I. et al. · Journal of Biological Chemistry · 2011 · 68 citations · Full text

Mechanistic insights into avian reovirus p17-modulated suppression of cell cycle CDK–cyclin complexes and enhancement of p53 and cyclin H interaction

Hung‐Chuan Chiu, Wei‐Ru Huang, Tsai‐Ling Liao et al. · Journal of Biological Chemistry · 2018 · 49 citations · Full text

Avian reovirus σA-modulated suppression of lactate dehydrogenase and upregulation of glutaminolysis and the mTOC1/eIF4E/HIF-1α pathway to enhance glycolysis and the TCA cycle for virus replication

Pei-I Chi, Wei‐Ru Huang, Hung‐Chuan Chiu et al. · Cellular Microbiology · 2018 · 46 citations

Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways

Wei‐Ru Huang, Hung‐Chuan Chiu, Tsai‐Ling Liao et al. · PLoS ONE · 2015 · 45 citations · Full text

Erk Signaling Pathways, Molecular Regulation, Viral Pathogenesis +22