Thinle Chodon

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Ramin Nazarian, Hubing Shi, Qi Wang et al. · Nature · 2010 · 2.1K citations

N-ras Upregulation, Medicine, Melanoma +7

Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy

Hubing Shi, Willy Hugo, Xiangju Kong et al. · Cancer Discovery · 2013 · 979 citations · Full text

Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance

Hubing Shi, Gatien Moriceau, Xiangju Kong et al. · Nature Communications · 2012 · 615 citations · Full text

Tumor Biology, Radiation Oncology, Engineering +10

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells

Chao Ma, Rong Fan, Habib Ahmad et al. · Nature Medicine · 2011 · 439 citations · Full text

Autoimmune Disease, Medicine, T-regulatory Cell +9

PD-1 Blockade Expands Intratumoral Memory T Cells

Antoni Ribas, Daniel Sanghoon Shin, Jesse M. Zaretsky et al. · Cancer Immunology Research · 2016 · 398 citations · Full text