Katrin J. Czogalla

Warfarin and vitamin K compete for binding to Phe55 in human VKOR

Katrin J. Czogalla, Arijit Biswas, Klara Höning et al. · Nature Structural & Molecular Biology · 2016 · 50 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces

Katrin J. Czogalla, Arijit Biswas, Ann‐Christin Wendeln et al. · Blood · 2013 · 49 citations

Medicine, Molecular Genetics, Pharmacology +7

Two enzymes catalyze vitamin K 2,3-epoxide reductase activity in mouse: VKORC1 is highly expressed in exocrine tissues while VKORC1L1 is highly expressed in brain

Michael Caspers, Katrin J. Czogalla, Kerstin Liphardt et al. · Thrombosis Research · 2015 · 39 citations · Full text

Life Sciences, Biochemistry, Enzymology +12

A new cell culture-based assay quantifies vitamin K 2,3-epoxide reductase complex subunit 1 function and reveals warfarin resistance phenotypes not shown by the dithiothreitol-driven VKOR assay

Andreas Fregin, Katrin J. Czogalla, Julia Gansler et al. · Journal of Thrombosis and Haemostasis · 2013 · 35 citations · Full text

Life Sciences, Biochemistry, Pharmacology +7

The Arg98Trp mutation in human VKORC1 causing VKCFD2 disrupts a di-arginine–based ER retention motif

Katrin J. Czogalla, Arijit Biswas, Simone Rost et al. · Blood · 2014 · 21 citations · Full text

Life Sciences, Genetics, Molecular Genetics +6