Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

Chengyu Liang, Pinghui Feng, Bonsu Ku, +4

Nature Cell Biology

Cell AutophagyMedicineAutophagyCell DeathSuppressor Activity +6

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

Chengyu Liang, Jong‐Soo Lee, Kyung‐Soo Inn, +8

Nature Cell Biology

Cell AutophagySignal TransductionCell SignalingNatural SciencesCell Trafficking +12

Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway

Gil Ju Seo, Aerin Yang, Brandon Tan, +7

Cell Reports

Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication

Junjie Zhang, Jun Zhao, Simin Xu, +15

Cell Host & Microbe

Viral ReplicationMolecular VirologyPathogenesisViral PathogenesisVirology +5

mRNA Degradation by the Virion Host Shutoff (Vhs) Protein of Herpes Simplex Virus: Genetic and Biochemical Evidence that Vhs Is a Nuclease

David N. Everly, Pinghui Feng, Shahzad I. Mian, +1

Journal of Virology

Inhibition of the ATM/p53 Signal Transduction Pathway by Kaposi's Sarcoma-Associated Herpesvirus Interferon Regulatory Factor 1

Young C. Shin, Hiroyuki Nakamura, Xiaozhen Liang, +4

Journal of Virology

Dna Damage StressCancer-associated VirusViral ImmunityViral PathogenesisImmunology +13

SARS-CoV-2 Nsp5 Demonstrates Two Distinct Mechanisms Targeting RIG-I and MAVS To Evade the Innate Immune Response

Yongzhen Liu, Chao Qin, Youliang Rao, +16

mBio

mRNA Decay during Herpes Simplex Virus (HSV) Infections: Protein-Protein Interactions Involving the HSV Virion Host Shutoff Protein and Translation Factors eIF4H and eIF4A

Pinghui Feng, David N. Everly, G. Sullivan Read

Journal of Virology

Viral ReplicationImmunologyMolecular BiologyTranslation Factors Eif4hViral Structural Protein +14

A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation

Jun Zhao, Yi Arial Zeng, Simin Xu, +10

Cell Host & Microbe

Viral ReplicationSystems BiologyHelicase DomainEngineeringNatural Sciences +8

STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2

Liting Zhang, Congqing Jiang, Yunhong Zhong, +18

Nature Cell Biology

Energy MetabolismBiochemistryAerobic GlycolysisCell SignalingNatural Sciences +9