Gary R. Freidenberg

Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects.

Gary R. Freidenberg, Robert R. Henry, Harald Klein et al. · Journal of Clinical Investigation · 1987 · 231 citations · Full text

Insulin Receptors, Insulin Receptor, Insulin Signaling +21

Reversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus. Effect of weight loss.

Gary R. Freidenberg, Donna Reichart, Jerrold M. Olefsky et al. · Journal of Clinical Investigation · 1988 · 195 citations · Full text

Insulin Resistance, Metabolic Syndrome, Obesity +15

Properties of a human insulin receptor with a COOH-terminal truncation. II. Truncated receptors have normal kinase activity but are defective in signaling metabolic effects.

Hiroshi Maegawa, Donald A. McClain, Gary R. Freidenberg et al. · Journal of Biological Chemistry · 1988 · 143 citations · Full text

Growth inhibition and increase of insulin receptors in antiestrogen-resistant T47DCO human breast cancer cells by progestins: implications for endocrine therapies.

Kathryn B. Horwitz, Gary R. Freidenberg · PubMed · 1985 · 138 citations

Insulin Receptors, Breast Oncology, Gynecology +17

Role of human skeletal muscle insulin receptor kinase in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity.

John J. Nolan, Gary R. Freidenberg, Robert R. Henry et al. · The Journal of Clinical Endocrinology & Metabolism · 1994 · 102 citations

Noninsulin-dependent Diabetes Mellitus, Tyrosine Kinase, Insulin Receptor +19