Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach, +96

Cell

BioinformaticsTumor BiologyRadiation OncologyFunctional GenomicsProject Drive +11

The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites

Mathias Jenal, Ran Elkon, Fabricio Loayza‐Puch, +9

Cell

ChromatinTranscriptional RegulationProtein Nuclear 1Polyadenylation SitesSuppresses Alternative Cleavage +8

E2F mediates enhanced alternative polyadenylation in proliferation

Ran Elkon, Jarno Drost, Gijs van Haaften, +4

Genome biology

Scavenger Chemokine (CXC Motif) Receptor 7 (CXCR7) Is a Direct Target Gene of HIC1 (Hypermethylated in Cancer 1)

Capucine Van Rechem, Brian R. Rood, Majid Touka, +9

Journal of Biological Chemistry

Quantitative analysis of cobblestone area-forming cells in bone marrow of patients with aplastic anemia by limiting dilution assay

Hubert Schrezenmeier, Mathias Jenal, F. Herrmann, +2

Blood

CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation

Jasmin Batliner, Maria Michela Mancarelli, Mathias Jenal, +4

Molecular Immunology

Transcriptional RegulationMyeloid DifferentiationGeneticsGene ExpressionMedicine +3

DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function

Adrian Britschgi, Emmanuelle Trinh, Mattia Rizzi, +5

Oncogene

Signal TransductionSignaling PathwayCell RegulationReceptor Tyrosine KinaseGenetics +7

<i>HIC1</i> tumour suppressor gene is suppressed in acute myeloid leukaemia and induced during granulocytic differentiation

Christian Britschgi, Mathias Jenal, Mattia Rizzi, +6

British Journal of Haematology

Hematological MalignancyMedicineMixed-phenotype Acute LeukemiaPromoter HypermethylationHematology +13

The Tumor Suppressor Gene <i>Hypermethylated in Cancer 1</i> Is Transcriptionally Regulated by E2F1

Mathias Jenal, Emmanuelle Trinh, Christian Britschgi, +8

Molecular Cancer Research

Cancer 1Cancer BiologyEpigeneticsTumor BiologyTranscriptional Regulation +15