Steven K. Wetter

Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

Ronghui Lin, Sigmond G. Johnson, Peter J. Connolly et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 126 citations · Full text

Medicinal Chemistry, Medicine, Pharmacological Agent +7

1-Acyl-1<i>H</i>-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors:  Synthesis and Evaluation of Biological Activities

Ronghui Lin, Peter J. Connolly, Shenlin Huang et al. · Journal of Medicinal Chemistry · 2005 · 126 citations · Full text

Selective Cdk1, Medicinal Chemistry, Representative Compound 3B +13

The <i>In vitro</i> and <i>In vivo</i> Effects of JNJ-7706621: A Dual Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases

Stuart L. Emanuel, Catherine A. Rugg, Robert H. Gruninger et al. · Cancer Research · 2005 · 122 citations · Full text

Dual Inhibitor, Cell Death, Total Cumulative Dose +22

4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation

Terry V. Hughes, Stuart L. Emanuel, Amanda K. Beck et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 45 citations · Full text

Medicine, Vegf-r2 Inhibitors, Rational Drug Design +4

N-Hydroxyurea and hydroxamic acid inhibitors of cyclooxygenase and 5-lipoxygenase

Peter J. Connolly, Steven K. Wetter, Kimberly N. Beers et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 42 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8