Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding

Mathias Eriksson, Ulla Uhlin, S. Ramaswamy, +4

Structure

Reductive StressBiochemistryNatural SciencesMolecular BiologyActive-site Cysteines Promotes +3

Recombinant protein expression and solubility screening in <i>Escherichia coli</i>: a comparative study

Nicholas S. Berrow, Konrad Büssow, Bruno Coutard, +13

Acta Crystallographica Section D Biological Crystallography

The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties

Thomas Näsström, Therese Fagerqvist, Mikael Barbu, +7

Free Radical Biology and Medicine

Neurodegenerative DiseasesFunctional PropertiesBiochemistryLipid PeroxidationDegenerative Pathology +8

Two Conserved Tyrosine Residues in Protein R1 Participate in an Intermolecular Electron Transfer in Ribonucleotide Reductase

Monica Ekberg, Margareta Sahlin, Mathias Eriksson, +1

Journal of Biological Chemistry

Aldo-keto ReductaseMolecular BiologyProtein R1 ParticipateChemical BiologyRedox Biology +15

Colony filtration blot: a new screening method for soluble protein expression in Escherichia coli

Tobias Cornvik, Sue‐Li Dahlroth, A. Magnusdottir, +4

Nature Methods

Protein ExpressionColony Filtration BlotSoluble Protein ExpressionBioanalysisBacteriology +7

Preserved Catalytic Activity in an Engineered Ribonucleotide Reductase R2 Protein with a Nonphysiological Radical Transfer Pathway

Monica Ekberg, Stephan Pötsch, Elin Sandin, +4

Journal of Biological Chemistry

BiochemistryRadical Transfer PathwayProtein FoldingNatural SciencesEnzyme Catalysis +10

Chemotherapeutic drug sensitivity testing of human leukemia cells in vitro using a semiautomated fluorometric assay.

Rolf Larsson, Peter Nygren, Monica Ekberg, +1

PubMed

An efficient and generic strategy for producing soluble human proteins and domains in <i>E. coli</i> by screening construct libraries

Tobias Cornvik, Sue‐Li Dahlroth, A. Magnusdottir, +5

Proteins Structure Function and Bioinformatics

A nationwide cohort study of the risk of chronic obstructive pulmonary disease in coeliac disease

Jonas F. Ludvigsson, Malin Inghammar, Monica Ekberg, +1

Journal of Internal Medicine

In Vivo Assay for Low-Activity Mutant Forms of <i>Escherichia coli</i> Ribonucleotide Reductase

Monica Ekberg, Pernilla Larsson Birgander, Britt‐Marie Sjöberg

Journal of Bacteriology

Molecular BiologyR1 Active SiteRedox BiologyProtein SynthesisStructure-function Enzyme Kinetics +14