Experimental Determination and System Level Analysis of Essential Genes in <i>Escherichia coli</i> MG1655

Svetlana Gerdes, Michael D. Scholle, John W. Campbell, +17

Journal of Bacteriology

EngineeringBacteriologyMolecular BiologyEscherichia ColiEssential Genes +18

A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner

Volker Schellenberger, Chia‐Wei Wang, Nathan C. Geething, +10

Nature Biotechnology

BiochemistryVivo Half-lifeProtein FoldingNatural SciencesPeptide Engineering +9

From Genetic Footprinting to Antimicrobial Drug Targets: Examples in Cofactor Biosynthetic Pathways

Svetlana Gerdes, Michael D. Scholle, Mark D’Souza, +13

Journal of Bacteriology

Structural, Kinetic and Proteomic Characterization of Acetyl Phosphate-Dependent Bacterial Protein Acetylation

Misty L. Kuhn, Bozena Zemaitaitis, Linda I. Hu, +10

PLoS ONE

Molecular BiologyAnalytical UltracentrifugationProtein SynthesisBiosynthesisNε-lysine Acetylation +15

Complete Reconstitution of the Human Coenzyme A Biosynthetic Pathway via Comparative Genomics

Matthew D. Daugherty, Boris M. Polanuyer, Michael Farrell, +4

Journal of Biological Chemistry

The <i>E. coli</i> sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites

Alaa Abouelfetouh, Misty L. Kuhn, Linda I. Hu, +10

MicrobiologyOpen

Molecular Recognition Properties of FN3 Monobodies that Bind the Src SH3 Domain

Ece Karatan, Matthew Merguerian, Zhaozhong Han, +3

Chemistry & Biology

Protein AssemblyBiochemistryProtein FoldingNatural SciencesMedicine +11

Discovery of SIRT3 Inhibitors Using SAMDI Mass Spectrometry

Kaushal Patel, John Sherrill, Milan Mrksich, +1

SLAS DISCOVERY

Medicinal ChemistryBiochemistryLysine ResiduesNatural SciencesMedicine +12

Gcg-XTEN: An Improved Glucagon Capable of Preventing Hypoglycemia without Increasing Baseline Blood Glucose

Nathan C. Geething, Wayne To, Benjamin Spink, +8

PLoS ONE

Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development

Cheng Liu, Sandro Boland, Michael D. Scholle, +10

Antiviral Research

Rhinovirus Hrv3c ProteaseImmunologyAntiviral DrugViral Structural ProteinCovid-19 +16