A model for transmission of the H3K27me3 epigenetic mark

Klaus Hansen, Adrian P. Bracken, Diego Pasini, +6

Nature Cell Biology

ChromatinH3k27me3 Epigenetic MarkChromatin RemodelingNatural SciencesGenetics +6

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition

John Arne Dahl, Inkyung Jung, Håvard Aanes, +16

Nature

ChromatinEmbryologyDevelopmental BiologyChromatin StructureChromatin Remodeling +10

Differential Effects of EGFR Ligands on Endocytic Sorting of the Receptor

Kirstine Roepstorff, Michael V. Grandal, Lasse Henriksen, +5

Traffic

An interactive environment for agile analysis and visualization of ChIP-sequencing data

Mads Lerdrup, Jens Vilstrup Johansen, Shuchi Agrawal‐Singh, +1

Nature Structural & Molecular Biology

EngineeringChip-sequencing DataInteractive Data ExplorationSoftware EngineeringSoftware Analysis +15

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia

Stefanie Göllner, Thomas Oellerich, Shuchi Agrawal‐Singh, +25

Nature Medicine

Histone ModificationsChromatinHematological MalignancyOncologyMedicine +9

Association with Membrane Protrusions Makes ErbB2 an Internalization-resistant Receptor

Anette M. Hommelgaard, Mads Lerdrup, Bo van Deurs

Molecular Biology of the Cell

Signal TransductionMedicineEndocytic PathwayReceptor (Biochemistry)Cell-matrix Interaction +13

REST–Mediated Recruitment of Polycomb Repressor Complexes in Mammalian Cells

Nikolaj Dietrich, Mads Lerdrup, Eskild Landt, +6

PLoS Genetics

Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals

Aditya Sankar, Faizaan Mohammad, Arun Kumar Sundaramurthy, +4

Nature Genetics

Histone ModificationsChromatinDevelopmental BiologyChromatin RemodelingEpigenetic Change +8

β-Catenin Regulates Primitive Streak Induction through Collaborative Interactions with SMAD2/SMAD3 and OCT4

Nina S. Funa, Karen A. Schachter, Mads Lerdrup, +6

Cell stem cell

Molecular PhysiologySignal TransductionSignaling PathwayMolecular RegulationNatural Sciences +7

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

Aditya Sankar, Mads Lerdrup, Adeel Manaf, +10

Nature Cell Biology

OocyteSignal TransductionDevelopmental BiologyCell RegulationMaternal-to-zygotic Transition +6