A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy

Christoph K. Stein‐Thoeringer, Neeraj Saini, Eli Zamir, +46

Nature Medicine

DysbiosisCancer ImmunosurveillanceMucosal ImmunologyClinical ResponsesImmunology +8

Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis

Taylor M. Halsey, Anusha Shirwaikar Thomas, Tomo Hayase, +19

Science Translational Medicine

R-Spondin1 expands Paneth cells and prevents dysbiosis induced by graft-versus-host disease

Eiko Hayase, Daigo Hashimoto, Kiminori Nakamura, +21

The Journal of Experimental Medicine

Chronic Inflammatory DiseasesDysbiosisMicrobial PathogensHost-microbe InteractionsImmunology +26

Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease

Eiko Hayase, Tomo Hayase, Mohamed A. Jamal, +37

Cell

Mucus-degrading Bacteroides LinkMedical MicrobiologyMicrobial DiseaseAntibioticsMicrobiology +4

Novel Ultrasonographic Scoring System of Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation

Mutsumi Nishida, Kaoru Kahata, Eiko Hayase, +9

Biology of Blood and Marrow Transplantation

Vitamin A–coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease

Tomohiro Yamakawa, Hiroyuki Ohigashi, Daigo Hashimoto, +7

Blood

Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment

Zaker Schwabkey, Diana H. Wiesnoski, Chia‐Chi Chang, +56

Science Translational Medicine

Intestinal goblet cells protect against GVHD after allogeneic stem cell transplantation via Lypd8

Takahide Ara, Daigo Hashimoto, Eiko Hayase, +17

Science Translational Medicine

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice

Hidetaka Uryu, Daigo Hashimoto, Koji Kato, +12

Blood

Ocular instillation of vitamin A–coupled liposomes containing HSP47 siRNA ameliorates dry eye syndrome in chronic GVHD

Hiroyuki Ohigashi, Daigo Hashimoto, Eiko Hayase, +7

Blood Advances