Karyn L. Sheaffer

DNA methylation is required for the control of stem cell differentiation in the small intestine

Karyn L. Sheaffer, Rinho Kim, Reina Aoki et al. · Genes & Development · 2014 · 202 citations · Full text

Genome-Wide Identification of Binding Sites Defines Distinct Functions for Caenorhabditis elegans PHA-4/FOXA in Development and Environmental Response

Mei Zhong, Wei Niu, Zhi John Lu et al. · PLoS Genetics · 2010 · 171 citations · Full text

Transcription Factor Pha-4, Genetics, Genomic Mechanism +20

The Target of Rapamycin Pathway Antagonizes pha-4/FoxA to Control Development and Aging

Karyn L. Sheaffer, Dustin L. Updike, Susan E. Mango · Current Biology · 2008 · 169 citations · Full text

Lifespan Extension, Developmental Biology, Signaling Pathway +8

DNA Hypomethylation Contributes to Genomic Instability and Intestinal Cancer Initiation

Karyn L. Sheaffer, Ellen N. Elliott, Klaus H. Kaestner · Cancer Prevention Research · 2016 · 150 citations · Full text

Chromatin, Genome Instability, Tumor Biology +14

The ‘de novo’ DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium

Ellen N. Elliott, Karyn L. Sheaffer, Klaus H. Kaestner · eLife · 2016 · 66 citations · Full text

Epigenetic Change, Genetics, Dna Methylation +16