Luis Martinez-Alsina

Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271

W. Gregory Roberts, Ethan Ung, Pamela Whalen et al. · Cancer Research · 2008 · 381 citations · Full text

Medicine, Oncology, Pharmacology +17

Discovery of PF-04449913, a Potent and Orally Bioavailable Inhibitor of Smoothened

Michael J. Munchhof, Qifang Li, Andrei Shavnya et al. · ACS Medicinal Chemistry Letters · 2011 · 160 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

Michael A. Brodney, Elizabeth M. Beck, Christopher R. Butler et al. · Journal of Medicinal Chemistry · 2015 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19

Charlotte Allerton, Joel T. Arcari, Lisa Aschenbrenner et al. · Journal of Medicinal Chemistry · 2024 · 73 citations · Full text

Medicine, Infectious Diseases, Pharmacology +15

Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design

Christopher R. Butler, Michael A. Brodney, Elizabeth Beck et al. · Journal of Medicinal Chemistry · 2015 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17