Kenji Ohgane

Discovery of Small Molecules that Induce the Degradation of Huntingtin

Shusuke Tomoshige, S. Nomura, Kenji Ohgane et al. · Angewandte Chemie International Edition · 2017 · 140 citations

A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate

H. YOSHIOKA, Hudson W. Coates, Ngee Kiat Chua et al. · Proceedings of the National Academy of Sciences · 2020 · 82 citations · Full text

Lipid Peroxidation, Squalene Epoxidase, Molecular Biology +16

Discovery of Oxysterol-Derived Pharmacological Chaperones for NPC1: Implication for the Existence of Second Sterol-Binding Site

Kenji Ohgane, Fumika Karaki, Kosuke Dodo et al. · Chemistry & Biology · 2013 · 74 citations

Oxysterol, Biochemistry, Medicine +8

Quantification of Gel Bands by an Image J Macro, Band/Peak Quantification Tool v1

Kenji Ohgane, H. YOSHIOKA · 2019 · 73 citations · Full text

Engineering, Microscopy, Gel Bands +22

Design, Synthesis, and Biological Evaluation of Novel Transrepression-Selective Liver X Receptor (LXR) Ligands with 5,11-Dihydro-5-methyl-11-methylene-6<i>H</i>-dibenz[<i>b</i>,<i>e</i>]azepin-6-one Skeleton

Atsushi Aoyama, Kaori Endo‐Umeda, Kenji Kishida et al. · Journal of Medicinal Chemistry · 2012 · 58 citations · Full text

Drug Target, Cellular Pharmacology, Systems Pharmacology +19