A Small Molecule that Promotes Cardiac Differentiation of Human Pluripotent Stem Cells under Defined, Cytokine- and Xeno-free Conditions

Itsunari Minami, Kohei Yamada, Tomomi G. Otsuji, +12

Cell Reports

A 3D Sphere Culture System Containing Functional Polymers for Large-Scale Human Pluripotent Stem Cell Production

Tomomi G. Otsuji, Bin Jiang, Azumi Yoshimura, +9

Stem Cell Reports

Tissue EngineeringRegenerative MedicineInduced Pluripotent Stem CellEngineeringMedicine +9

Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A

Masataka Fujiwara, Peishi Yan, Tomomi G. Otsuji, +17

PLoS ONE

Cardiac MuscleCardiac Progenitor CellsCardiac RegenerationIpsc Differentiation SystemStem Cell Biology +20

Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: Qualitative effects on electrophysiological responses to drugs

Tomomi G. Otsuji, Itsunari Minami, Yuko Kurose, +3

Stem Cell Research

Cardiac MuscleQualitative EffectsCardiac Progenitor CellsBiomedical EngineeringElectrophysiological Responses +21

Targeted chromosome elimination from ES-somatic hybrid cells

Hiroyuki Matsumura, Masako Tada, Tomomi G. Otsuji, +4

Nature Methods

ChromatinCytogeneticsGeneticsGenetic EngineeringChromosome Biology +3

Monitoring for dynamic biological processing by intramolecular bioluminescence resonance energy transfer system using secreted luciferase

Tomomi G. Otsuji, Emiko Okuda‐Ashitaka, Satoshi Kojima, +3

Analytical Biochemistry

EngineeringBioluminescenceBiosensing SystemsDynamic Biological ProcessingBioprocess Monitoring +6

Dynamic Link between Histone H3 Acetylation and an Increase in the Functional Characteristics of Human ESC/iPSC-Derived Cardiomyocytes

Tomomi G. Otsuji, Yuko Kurose, Hirofumi Suemori, +2

PLoS ONE

Tissue EngineeringCardiac MuscleDynamic LinkEngineeringEpigenetic Change +26

Cardiomyocytes develop from anterior primitive streak cells induced by β‐catenin activation and the blockage of BMP signaling in hESCs

Kaori Yamauchi, Tomoyuki Sumi, Itsunari Minami, +4

Genes to Cells

Rapid Induction of Large Chromosomal Deletions by a Cre/Inverted loxP System in Mouse ES Cell Hybrids

Tomomi G. Otsuji, Hiroyuki Matsumura, Tatsuya Suzuki, +3

Journal of Molecular Biology

Knockout MouseChromatinRapid InductionMedicineGenetics +7