Kristine Muller

Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents

Roland W. Bürli, Han Xu, Xiaoming Zou et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 125 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Identification of <i>N</i>-(4-((1<i>R</i>,3<i>S</i>,5<i>S</i>)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies

Matthew T. Burger, Gisele Nishiguchi, Wooseok Han et al. · Journal of Medicinal Chemistry · 2015 · 76 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Discovery of AMG 369, a Thiazolo[5,4-<i>b</i>]pyridine Agonist of S1P₁ and S1P₅

Victor J. Cee, Mike Frohn, Brian A. Lanman et al. · ACS Medicinal Chemistry Letters · 2010 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors

Matthew T. Burger, Wooseok Han, Jiong Lan et al. · ACS Medicinal Chemistry Letters · 2013 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1α prolyl hydroxylase-2 inhibitors

Mike Frohn, Vellarkad N. Viswanadhan, Alexander J. Pickrell et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11