Endothelial-to-mesenchymal transition drives atherosclerosis progression

Pei‐Yu Chen, Lingfeng Qin, Nicolas Baeyens, +6

Journal of Clinical Investigation

Vascular DiseaseImmunologyInflammationFibroblast Growth FactorEndothelial-to-mesenchymal Transition Drives +19

Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis

Pei‐Yu Chen, Lingfeng Qin, Guangxin Li, +24

Nature Metabolism

InflammationVascular DiseaseCardiovascular DiseaseImmunologyEndothelial Dysfunction +6

FGF Regulates TGF-β Signaling and Endothelial-to-Mesenchymal Transition via Control of let-7 miRNA Expression

Pei‐Yu Chen, Lingfeng Qin, Carmen Barnes, +12

Cell Reports

Ten-Eleven Translocation-2 (TET2) Is a Master Regulator of Smooth Muscle Cell Plasticity

Renjing Liu, Jin Yu, Wai Ho Tang, +6

Circulation

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis

Wei Li, Qingle Li, Yang Jiao, +10

Journal of Clinical Investigation

Tgfbr2 DisruptionDevelopmental BiologyAngiogenesisMolecular PhysiologySmooth Muscle Promotes +12

Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells

Ashish Misra, Zhonghui Feng, Rachana R. Chandran, +9

Nature Communications

Smooth Muscle Cell Reprogramming in Aortic Aneurysms

Pei-Yu Chen, Lingfeng Qin, Guangxin Li, +22

Cell stem cell

MechanobiologyCardiac ReprogrammingVascular AdaptationVascular BiologyAortic Aneurysms +4

Tissue-Engineered Vascular Grafts with Advanced Mechanical Strength from Human iPSCs

Jiesi Luo, Lingfeng Qin, Liping Zhao, +19

Cell stem cell

MechanobiologyRegenerative MedicineTissue EngineeringVascular GraftsVascular Tissue Engineering +12

Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation

Huanjiao Jenny Zhou, Lingfeng Qin, Haifeng Zhang, +13

Nature Medicine

Developmental BiologyAngiogenesisVascular MalformationPathologyCcm3 Deficiency Contributes +7

Alloantibody and Complement Promote T Cell–Mediated Cardiac Allograft Vasculopathy Through Noncanonical Nuclear Factor-κB Signaling in Endothelial Cells

Dan Jane‐wit, Thomas D. Manes, Tai Yi, +9

Circulation