Endothelial-to-mesenchymal transition drives atherosclerosis progression

Pei‐Yu Chen, Lingfeng Qin, Nicolas Baeyens, +6

Journal of Clinical Investigation

Vascular DiseaseImmunologyInflammationFibroblast Growth FactorEndothelial-to-mesenchymal Transition Drives +19

Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis

Pei‐Yu Chen, Lingfeng Qin, Guangxin Li, +24

Nature Metabolism

InflammationVascular DiseaseCardiovascular DiseaseImmunologyEndothelial Dysfunction +6

Smooth Muscle Cell Reprogramming in Aortic Aneurysms

Pei-Yu Chen, Lingfeng Qin, Guangxin Li, +22

Cell stem cell

MechanobiologyCardiac ReprogrammingVascular AdaptationVascular BiologyAortic Aneurysms +4

Caveolin-1 Regulates Atherogenesis by Attenuating Low-Density Lipoprotein Transcytosis and Vascular Inflammation Independently of Endothelial Nitric Oxide Synthase Activation

Cristina M. Ramírez, Xinbo Zhang, Chirosree Bandyopadhyay, +18

Circulation

Tissue-Engineered Vascular Grafts with Advanced Mechanical Strength from Human iPSCs

Jiesi Luo, Lingfeng Qin, Liping Zhao, +19

Cell stem cell

MechanobiologyRegenerative MedicineTissue EngineeringVascular GraftsVascular Tissue Engineering +12

Circulating MicroRNA-21 Is a Potential Diagnostic Biomarker in Gastric Cancer

Guangxin Li, Zeyou Wang, Yongliang Yao, +3

Disease Markers

Tumor BiologyOncologyMedicineMir-21 LevelsImmunology +12

Mitochondrial unfolded protein response gene <i>Clpp</i> is required to maintain ovarian follicular reserve during aging, for oocyte competence, and development of pre‐implantation embryos

Tianren Wang, Elnur Babayev, Zongliang Jiang, +5

Aging Cell

Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells

Jiajia Cui, Lingfeng Qin, Junwei Zhang, +7

Nature Communications

Chronic mTOR activation induces a degradative smooth muscle cell phenotype

Guangxin Li, Mo Wang, Alexander W. Caulk, +20

Journal of Clinical Investigation

Muscle FunctionChronic Mtor ActivationImmunologyCell DeathCell Proliferation +27

2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2

Li Ma, Guangxin Li, Huaqiang Zhu, +7

Cancer Letters

OncologyHepatologyMedicinePathology2-Methoxyestradiol Synergizes +4