Ayşegül Özen

AÖ

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Publications

Citations

1.4K

H-Index

Active since

2005

Affiliations

University of Massachusetts Chan Medical School(Current)

Boğaziçi University

Gene Therapy Laboratory

Blueprint Medicines (United States)

Ayşegül Özen is an author at University of Massachusetts Chan Medical School specializing in life sciences, molecular biology, and structural biology.

ORCID

Publications per year

2005–2024

Publications

The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors

Keith P. Romano, Akbar Ali, Djadé I. Soumana et al. · PLoS Pathogens · 2012 · 223 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2

Scott A. Foster, Daniel M. Whalen, Ayşegül Özen et al. · Cancer Cell · 2016 · 216 citations · Full text

Medicine, Genetics, Oncology +14

Discovery of BLU-945, a Reversible, Potent, and Wild-Type-Sparing Next-Generation EGFR Mutant Inhibitor for Treatment-Resistant Non-Small-Cell Lung Cancer

Meredith S. Eno, Jason D. Brubaker, John E. Campbell et al. · Journal of Medicinal Chemistry · 2022 · 160 citations · Full text

Medicine, Oncology, Pharmacology +14

Molecular Basis for Drug Resistance in HIV-1 Protease

Akbar Ali, R.M. Bandaranayake, Yufeng Cai et al. · Viruses · 2010 · 155 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Clusters of isoleucine, leucine, and valine side chains define cores of stability in high‐energy states of globular proteins: Sequence determinants of structure and stability

Sagar V. Kathuria, Yvonne Chan, R. Paul Nobrega et al. · Protein Science · 2015 · 89 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

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