J E Darnell

Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.

Christian Schindler, Xiuping Fu, T Improta et al. · Proceedings of the National Academy of Sciences · 1992 · 665 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain.

Curt M. Horvath, J E Darnell · Genes & Development · 1995 · 539 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.

David E. Levy, Daniel S. Kessler, Richard Pine et al. · Genes & Development · 1989 · 488 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either.

Richard Pine, Thomas Decker, Daniel S. Kessler et al. · Molecular and Cellular Biology · 1990 · 331 citations

Life Sciences, Genetics, Molecular Biology +17

Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3.

Sajjad A. Qureshi, M. Salditt-Georgieff, J E Darnell · Proceedings of the National Academy of Sciences · 1995 · 237 citations

Life Sciences, Biochemistry, Molecular Biology +13