Richard Pine

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.

David T. Levy, Daniel S. Kessler, Richard Pine et al. · Genes & Development · 1988 · 572 citations · Full text

Genetics, Molecular Biology, Consensus Element Yagtttc +19

Requirement for MAP Kinase (ERK2) Activity in Interferon α- and Interferon β-Stimulated Gene Expression Through STAT Proteins

Michael David, Emanuel Petricoin, Christopher D. Benjamin et al. · Science · 1995 · 545 citations

Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.

David T. Levy, Daniel S. Kessler, Richard Pine et al. · Genes & Development · 1989 · 487 citations · Full text

Immunology, Transcriptional Regulation, Signaling Pathway +16

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

Richard Pine, Antony Canova, Christian Schindler · The EMBO Journal · 1994 · 355 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +12

Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either.

Richard Pine, Thomas Decker, Daniel S. Kessler et al. · Molecular and Cellular Biology · 1990 · 331 citations

Alpha Interferon, Transcriptional Regulation, Signal Transduction +15