Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.

David T. Levy, Daniel S. Kessler, Richard Pine, +2

Genes & Development

GeneticsMolecular BiologyConsensus Element YagtttcMolecular GeneticsGene Regulatory Network +17

Requirement for MAP Kinase (ERK2) Activity in Interferon α- and Interferon β-Stimulated Gene Expression Through STAT Proteins

Michael David, Emanuel Petricoin, Christopher D. Benjamin, +3

Science

Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.

David T. Levy, Daniel S. Kessler, Richard Pine, +1

Genes & Development

ImmunologyTranscriptional RegulationSignaling PathwayCell RegulationPositive Regulator +14

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

Richard Pine, Antony Canova, Christian Schindler

The EMBO Journal

Transcriptional RegulationSignal TransductionSignaling PathwayIfn GammaReceptor Tyrosine Kinase +10

Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either.

Richard Pine, Thomas Decker, Daniel S. Kessler, +2

Molecular and Cellular Biology

Alpha InterferonTranscriptional RegulationSignal TransductionDevelopmental BiologySignaling Pathway +13

Endothelial Interferon Regulatory Factor 1 Cooperates with NF-κB as a Transcriptional Activator of Vascular Cell Adhesion Molecule 1

Andrew S. Neish, Margaret Read, Dimitris Thanos, +3

Molecular and Cellular Biology

Activation of STAT4 by IL-12 and IFN-α: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation

S S Cho, Chris M. Bacon, Chitra Sudarshan, +4

The Journal of Immunology

Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs

Lanbo Shi, Hugh Salamon, Eliseo A. Eugenín, +3

Scientific Reports

Activation of the p38 Mitogen-activated Protein Kinase by Type I Interferons

Shahab Uddin, Beata Majchrzak, Joanna Woodson, +6

Journal of Biological Chemistry

STF-IL-4: a novel IL-4-induced signal transducing factor.

Christian Schindler, H. Kashleva, Alessandra B. Pernis, +2

The EMBO Journal

InflammationCytokineSignal TransductionImmunologyImmune System +3