Ana Galesic

α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson’s disease

Paul M. Levine, Ana Galesic, Aaron T. Balana et al. · Proceedings of the National Academy of Sciences · 2019 · 236 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

O-GlcNAcylation of α-Synuclein at Serine 87 Reduces Aggregation without Affecting Membrane Binding

Yuka E. Lewis, Ana Galesic, Paul M. Levine et al. · ACS Chemical Biology · 2017 · 105 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein

Paul M. Levine, Cesar A. De Leon, Ana Galesic et al. · Bioorganic & Medicinal Chemistry · 2017 · 46 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Synthesis of a Bis-thio-acetone (BTA) Analogue of the Lysine Isopeptide Bond and its Application to Investigate the Effects of Ubiquitination and SUMOylation on α-Synuclein Aggregation and Toxicity

Yuka E. Lewis, Tharindumala Abeywardana, Yu Lin et al. · ACS Chemical Biology · 2016 · 35 citations

Life Sciences, Biochemistry, Molecular Biology +10

Comparison of <i>N</i>-Acetyl-Glucosamine to Other Monosaccharides Reveals Structural Differences for the Inhibition of α-Synuclein Aggregation

Ana Galesic, Ananya Rakshit, Giuliano Cutolo et al. · ACS Chemical Biology · 2021 · 31 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17