The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development

Ana Ortega-Molina, Isaac W. Boss, Andrés Canela, +25

Nature Medicine

Histone ModificationsChromatinLymphoid NeoplasiaGene Expression ProgramChromatin Remodeling +7

The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

Deqing Hu, Xin Gao, Marc A. Morgan, +3

Molecular and Cellular Biology

Histone ModificationsEpigenetic ChangeGeneticsCompass Family MembersGenomic Mechanism +18

Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells

S Liu, Hongyu Zhang, Mei Li, +5

Cell Death and Differentiation

Signal TransductionItt-like MotifCell RegulationCell SignalingMedicine +8

A Role for H3K4 Monomethylation in Gene Repression and Partitioning of Chromatin Readers

Jemmie Cheng, Roy Blum, Christopher Bowman, +4

Molecular Cell

Histone ModificationsChromatinChromatin RemodelingNatural SciencesGenetics +13

Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion

Zhenrui Li, Pengxu Qian, Wanqing Shao, +28

Cell Research

Radiation OncologyHealth SciencesMedicineStem Cell MobilizationStem Cell Transplantation +7

Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates

Wei Wang, Chi‐Kuo Hu, An Zeng, +14

Science

Integrator Regulates Transcriptional Initiation and Pause Release following Activation

Alessandro Gardini, David Baillat, Matteo Cesaroni, +6

Molecular Cell

Transcriptional RegulationSignal TransductionGene RegulationSystems BiologyMedicine +4

The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells

Deqing Hu, Alexander S. Garruss, Xin Gao, +4

Nature Structural & Molecular Biology

Stem Cell BiologyChromatinTranscriptional RegulationDevelopmental BiologyMll2 Branch +11

A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer

Damiano Fantini, Alexander P. Glaser, Kalen Rimar, +18

Oncogene

Promoter bivalency favors an open chromatin architecture in embryonic stem cells

Glòria Mas Martín, Enrique Blanco, Cecilia Ballaré, +8

Nature Genetics

GeneticsEpigeneticsTranscriptional RegulationOpen Chromatin ArchitectureStem Cells +14