Sumit Prakash

An unstructured initiation site is required for efficient proteasome-mediated degradation

Sumit Prakash, Lin Tian, Kevin S. Ratliff et al. · Nature Structural & Molecular Biology · 2004 · 466 citations

Protein Chemistry, Protein Assembly, Biochemistry +11

ATP-Dependent Proteases Degrade Their Substrates by Processively Unraveling Them from the Degradation Signal

Cheolju Lee, Michael P. Schwartz, Sumit Prakash et al. · Molecular Cell · 2001 · 400 citations · Full text

Protein Function, Biochemistry, Protein Folding +12

USP7 small-molecule inhibitors interfere with ubiquitin binding

Lorna Kategaya, Paola Di Lello, Lionel Rougé et al. · Nature · 2017 · 332 citations · Full text

Molecular Docking, Ubiquitin Binding, Drug Target +7

Lack of a Robust Unfoldase Activity Confers a Unique Level of Substrate Specificity to the Universal AAA Protease FtsH

Christophe Herman, Sumit Prakash, Chi Zen Lu et al. · Molecular Cell · 2003 · 184 citations · Full text

Protein Assembly, Biochemistry, Protein Folding +10

Defining the geometry of the two-component proteasome degron

Tomonao Inobe, Susan Fishbain, Sumit Prakash et al. · Nature Chemical Biology · 2011 · 181 citations · Full text

Two-component Proteasome Degron, Protein Assembly, Protein Folding +8