Multi-omic measurements of heterogeneity in HeLa cells across laboratories

Yansheng Liu, Mi Yang, Torsten Mueller, +20

Nature Biotechnology

HistocompatibilityMulti-omic MeasurementsMedicineBioanalysisCell Culture +6

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane

Martin Mehnert, Thomas Sommer, Ernst Jarosch

Nature Cell Biology

Signal TransductionNatural SciencesMolecular BiologyMembrane BiologyMisfolded Proteins +8

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, +10

Molecular Cell

Combining Rapid Data Independent Acquisition and CRISPR Gene Deletion for Studying Potential Protein Functions: A Case of HMGN1

Martin Mehnert, Wenxue Li, Chongde Wu, +2

PROTEOMICS

Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer

Arthur Dondi, Ulrike Lischetti, Francis Jacob, +129

Nature Communications

The interplay of Hrd3 and the molecular chaperone system ensures efficient degradation of malfolded secretory proteins

Martin Mehnert, Franziska Sommermeyer, Maren Berger, +5

Molecular Biology of the Cell

Receptor Hrd3Protein SecretionProtein AssemblyProteasomeMolecular Biology +18

Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes

Martin Mehnert, Rodolfo Ciuffa, Fabian Frommelt, +5

Nature Communications

Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia

Rebekka Wegmann, Ximena Bonilla, Ruben Casanova, +154

Nature Communications

Analysis of the interferon-γ-induced secretome of intestinal endothelial cells: putative impact on epithelial barrier dysfunction in IBD

Elisabeth Naschberger, Christian Flierl, Jing‐Hao Huang, +9

Frontiers in Cell and Developmental Biology

Chronic Inflammatory DiseasesHiec ProteinsGastrointestinal PharmacologyImmune RegulationGastroenterology +21

Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics

Rodolfo Ciuffa, Federico Uliana, Jonathan Mannion, +10

Proceedings of the National Academy of Sciences

ImmunologyMolecular BiologyInflammationProteomic TechnologySystems Insights +21