Sangeeth M. George

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

Alexander C. Huang, Michael A. Postow, Robert J. Orlowski et al. · Nature · 2017 · 1.7K citations · Full text

Life Sciences, Immunology, Oncology +16

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan, Josephine R. Giles, Sierra J. McDonald et al. · Nature · 2019 · 1.6K citations

Life Sciences, Immunology, Molecular Biology +12

A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

Alexander C. Huang, Robert Orlowski, Xiaowei Xu et al. · Nature Medicine · 2019 · 702 citations

Medicine, Clinical Sciences, Oncology +17

Nivolumab plus ipilimumab versus sunitinib for first-line treatment of advanced renal cell carcinoma: extended 8-year follow-up results of efficacy and safety from the phase III CheckMate 214 trial

Nizar M. Tannir, Laurence Albigès, David F. McDermott et al. · Annals of Oncology · 2024 · 192 citations · Full text

Medicine, Oncology, Pharmacotherapy +14

Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers

Josephine R. Giles, Sasikanth Manne, Elizabeth Freilich et al. · Immunity · 2022 · 122 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14