Megan E. Capozzi

Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist

Francis S. Willard, Jonathan D. Douros, M Gabe et al. · JCI Insight · 2020 · 439 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Insulin Signaling +20

β Cell tone is defined by proglucagon peptides through cAMP signaling

Megan E. Capozzi, Berit Svendsen, Sara E. Encisco et al. · JCI Insight · 2019 · 244 citations · Full text

Paracrine Interactions, Glucose Tolerance, Camp Signaling +24

Glucagon lowers glycemia when β cells are active

Megan E. Capozzi, Jacob B. Wait, Jepchumba Koech et al. · JCI Insight · 2019 · 159 citations · Full text

Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway

Sophie L. Lewandowski, Rebecca Cardone, Hannah R. Foster et al. · Cell Metabolism · 2020 · 147 citations · Full text

Metabolic Syndrome, Signal Transduction, Biochemistry +13

GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells

Kimberley El, Sarah M. Gray, Megan E. Capozzi et al. · Science Advances · 2021 · 121 citations · Full text