James Osborne

Catalytic Enantioselective Intermolecular Hydroacylation: Rhodium-Catalyzed Combination of β-<i>S</i>-Aldehydes and 1,3-Disubstituted Allenes

James Osborne, Helen E. Randell‐Sly, Gordon S. Currie et al. · Journal of the American Chemical Society · 2008 · 153 citations

Cross-coupling Reaction, Me-duphos Ligand Promotes, Engineering +11

The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eμ-MYC driven B-cell lymphoma

Mike I. Walton, Paul D. Eve, Angela Hayes et al. · Oncotarget · 2015 · 68 citations · Full text

Immunology, Ps296 Chk1, Pathology +19

Binder addition methods and binder distribution in high shear and fluidised bed granulation

James Osborne, Robert Sochon, J. Cartwright et al. · Process Safety and Environmental Protection · 2010 · 48 citations

Seabed Liquefaction, Engineering, Mechanical Engineering +7

Rhodium-catalysed hydroacylation or reductive aldol reactions: a ligand dependent switch of reactivity

James Osborne, Michael C. Willis · Chemical Communications · 2008 · 45 citations

Intermolecular rhodium catalyzed hydroacylation of allenes: the regioselective synthesis of β,γ-unsaturated ketones

Helen E. Randell‐Sly, James Osborne, Robert L. Woodward et al. · Tetrahedron · 2009 · 38 citations

Chemical Engineering, Engineering, Organic Chemistry +7