Susan Edwards

Monocarboxylate transporter MCT1 is a target for immunosuppression

Clare Murray, Raymond J. Hutchinson, John R. Bantick et al. · Nature Chemical Biology · 2005 · 248 citations · Full text

Molecular Physiology, Signal Transduction, Monocarboxylate Transporter Mct1 +8

The Specific Monocarboxylate Transporter-1 (MCT-1) Inhibitor, AR-C117977, Induces Donor-Specific Suppression, Reducing Acute and Chronic Allograft Rejection in the Rat

Henrik Ekberg, Zhongquan Qi, Clara Påhlman et al. · Transplantation · 2007 · 35 citations

Biological characterization of a novel class of toll‐like receptor 7 agonists designed to have reduced systemic activity

Mark Biffen, Hiroyuki Matsui, Susan Edwards et al. · British Journal of Pharmacology · 2011 · 34 citations · Full text

Inflammatory Lung Disease, Immunotoxicology, Lung Inflammation +23

TLR7 Stimulation of APCs Results in Inhibition of IL-5 through Type I IFN and Notch Signaling Pathways in Human Peripheral Blood Mononuclear Cells

Susan Edwards, Carolyn Jones, Andrew J. Leishman et al. · The Journal of Immunology · 2013 · 26 citations

T-regulatory Cell, Immunology, Immune Regulation +25

Mechanism of Action of Inhibition of Allergic Immune Responses by a Novel Antedrug TLR7 Agonist

Hiroyuki Matsui, Hideyuki Tomizawa, Kazuo Eiho et al. · The Journal of Immunology · 2012 · 18 citations

Asthma, Inflammatory Lung Disease, Lung Inflammation +22