Mark Biffen

CD45 tyrosine phosphatase-activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx.

Masahiro Shiroo, Lindsey K. Goff, Mark Biffen et al. · The EMBO Journal · 1992 · 175 citations · Full text

Calcium Influx, Signal Transduction, Molecular Physiology +12

The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.

Mark Biffen, D.F. McMichael-Phillips, Thomas R. Larson et al. · The EMBO Journal · 1994 · 55 citations · Full text

Signal Transduction, Cd4-associated P56lck Tyrosine, Receptor Tyrosine Kinase +12

<i>Haemophilus influenzae</i> Induces Neutrophil Necrosis

Emma J. Naylor, Denise Bakstad, Mark Biffen et al. · American Journal of Respiratory Cell and Molecular Biology · 2007 · 46 citations

Biological characterization of a novel class of toll‐like receptor 7 agonists designed to have reduced systemic activity

Mark Biffen, Hiroyuki Matsui, Susan Edwards et al. · British Journal of Pharmacology · 2011 · 34 citations · Full text

Inflammatory Lung Disease, Immunotoxicology, Lung Inflammation +23

Vasopressin-stimulated Ca2+ influx in rat hepatocytes is inhibited in high-K+ medium

Anne Savage, Mark Biffen, Bronwen Martin · Biochemical Journal · 1989 · 34 citations · Full text

Electrolyte Disorder, High K+, Cellular Physiology +17