Clare Murray

CD147 subunit of lactate/H ⁺ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

Renaud Le Floch, Johanna Chiche, Ibtissam Marchiq et al. · Proceedings of the National Academy of Sciences · 2011 · 413 citations

Medicine, Cell Biology, Oncology +17

AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7–10

Matthew J. Ovens, Andrew Davies, Marieangela C. Wilson et al. · Biochemical Journal · 2009 · 263 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Monocarboxylate transporter MCT1 is a target for immunosuppression

Clare Murray, Raymond J. Hutchinson, John R. Bantick et al. · Nature Chemical Biology · 2005 · 249 citations · Full text

Life Sciences, Immunology, Molecular Biology +6

Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt’s lymphoma anti-tumor activity

Nicola J. Curtis, Lorraine Mooney, Lorna Hopcroft et al. · Oncotarget · 2017 · 158 citations · Full text

Medicine, Oncology, Pharmacology +13

The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein

Matthew J. Ovens, Christine Manoharan, Marieangela C. Wilson et al. · Biochemical Journal · 2010 · 89 citations · Full text

Life Sciences, Biochemistry, Pharmacology +8