Renaud Le Floch

CD147 subunit of lactate/H ⁺ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

Renaud Le Floch, Johanna Chiche, Ibtissam Marchiq et al. · Proceedings of the National Academy of Sciences · 2011 · 405 citations

Genetic Disruption of Lactate/H+ Symporters (MCTs) and Their Subunit CD147/BASIGIN Sensitizes Glycolytic Tumor Cells to Phenformin

Ibtissam Marchiq, Renaud Le Floch, Danièle Roux et al. · Cancer Research · 2014 · 168 citations

Genetic Disruption, Chemoprevention Strategy, Biochemistry +13

Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1

Kym Sutton, Shaista Hayat, N-M Chau et al. · Oncogene · 2007 · 64 citations

Differential Requirement, Selective Inhibition, Reductive Stress +10

Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status

Sara Granja, Ibtissam Marchiq, Renaud Le Floch et al. · Oncotarget · 2014 · 59 citations · Full text

Nm23-M2/NDP kinase B induces endogenous c-myc and nm23-M1/NDP kinase A overexpression in BAF3 cells. Both NDP kinases protect the cells from oxidative stress-induced death

Sandrine Arnaud‐Dabernat, Karine Massé, Moneïm Smani et al. · Experimental Cell Research · 2004 · 34 citations

Nm23-m1/ndp Kinase, Redox Signaling, Cell Regulation +10