Peter Kühnen

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

Peter Kühnen, Karine Clément, Susanna Wiegand et al. · New England Journal of Medicine · 2016 · 470 citations

Medicine, Endocrinology, Pharmacology +17

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

Karine Clément, Heike Biebermann, I. Sadaf Farooqi et al. · Nature Medicine · 2018 · 310 citations

Life Sciences, Endocrinology, Genetics +12

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans

Federica Buonocore, Peter Kühnen, Jenifer P. Suntharalingham et al. · Journal of Clinical Investigation · 2017 · 170 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity

Peter Kühnen, Daniela Handke, Robert A. Waterland et al. · Cell Metabolism · 2016 · 133 citations · Full text

Medicine, Genetics, Molecular Genetics +14

Structures of active melanocortin-4 receptor–Gs-protein complexes with NDP-α-MSH and setmelanotide

Nicolas Heyder, Gunnar Kleinau, David Speck et al. · Cell Research · 2021 · 95 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17