Kazuhisa Uchida

The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity

Toyohide Shinkawa, Kazuyasu Nakamura, Naoko Yamane et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

Life Sciences, Biochemistry, Immunology +17

Establishment of <i>FUT8</i> knockout Chinese hamster ovary cells: An ideal host cell line for producing completely defucosylated antibodies with enhanced antibody‐dependent cellular cytotoxicity

Naoko Yamane‐Ohnuki, Satoko Kinoshita, Miho Inoue‐Urakubo et al. · Biotechnology and Bioengineering · 2004 · 574 citations

Pharmacy, Biochemistry, Immunology +16

Fucose Depletion from Human IgG1 Oligosaccharide Enhances Binding Enthalpy and Association Rate Between IgG1 and FcγRIIIa

Akira Okazaki, Emi Shoji-Hosaka, Kazuyasu Nakamura et al. · Journal of Molecular Biology · 2004 · 337 citations

Life Sciences, Biochemistry, Immunology +13

Defucosylated Chimeric Anti-CC Chemokine Receptor 4 IgG1 with Enhanced Antibody-Dependent Cellular Cytotoxicity Shows Potent Therapeutic Activity to T-Cell Leukemia and Lymphoma

Rinpei Niwa, Emi Shoji-Hosaka, Mikiko Sakurada et al. · Cancer Research · 2004 · 326 citations

Life Sciences, Immunology, Oncology +13

IgG subclass-independent improvement of antibody-dependent cellular cytotoxicity by fucose removal from Asn297-linked oligosaccharides

Rinpei Niwa, Akito Natsume, Aya Uehara et al. · Journal of Immunological Methods · 2005 · 242 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17